|Application ||WB, E|
|Calculated MW||88106 Da|
|Other Names||Tyrosine-protein phosphatase non-receptor type 12, 22.214.171.124, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1, PTPN12|
|Target/Specificity||This PTPN12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 681-714 amino acids from human PTPN12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PTPN12 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.|
|Cellular Location||Cytoplasm. Cell projection, podosome|
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Provided below are standard protocols that you may find useful for product applications.
Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.
Takekawa M.,et al.Biochem. Biophys. Res. Commun. 189:1223-1230(1992).
Yang Q.,et al.J. Biol. Chem. 268:6622-6628(1993).
Yang Q.,et al.J. Biol. Chem. 268:17650-17650(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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