|Application ||WB, E|
|Other Accession||Q9JLJ0, P0C0T0|
|Calculated MW||17107 Da|
|Other Names||Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, p53-induced gene 7 protein, LITAF, PIG7, SIMPLE|
|Target/Specificity||This LITAF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the human LITAF.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LITAF Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF- alpha) gene expression.|
|Cellular Location||Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with membranes of lysosomes|
|Tissue Location||Ubiquitously and abundantly expressed. Expressed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF- alpha) gene expression.
Polyak K.,et al.Nature 389:300-306(1997).
Myokai F.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:4518-4523(1999).
Moriwaki Y.,et al.J. Biol. Chem. 276:23065-23076(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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