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INTS6 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - INTS6 Antibody (N-Term) AP21956a
    All lanes : Anti-INTS6 Antibody (N-Term) at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 100 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UL03
Other Accession Q5JSJ4, Q8BND4, Q2TAF4, Q5U4W6, Q7SYD9, Q6PCM2
Reactivity Human
Predicted Xenopus, Mouse, Zebrafish
Host Rabbit
Clonality polyclonal
Isotype IgG1,K
Calculated MW 100390 Da
Additional Information
Gene ID 26512
Other Names Integrator complex subunit 6, Int6, DBI-1, Protein DDX26, Protein deleted in cancer 1, DICE1, INTS6, DBI1, DDX26, DDX26A
Target/Specificity This INTS6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from human INTS6.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsINTS6 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INTS6
Synonyms DBI1, DDX26, DDX26A
Function Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
Cellular Location Nucleus.
Tissue Location Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Citations (0)

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Background

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.

References

Wieland I.,et al.Oncogene 18:4530-4537(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Dunham A.,et al.Nature 428:522-528(2004).
Hoff H.B. III,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Wieland I.,et al.Oncol. Res. 12:491-500(2001).

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$ 99.00
Cat# AP21956a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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