|Application ||WB, E|
|Other Accession||Q5EAA5, Q5R7E2|
|Calculated MW||11341 Da|
|Other Names||T-cell leukemia translocation-altered gene protein, T-cell leukemia translocation-associated gene protein, TCTA|
|Target/Specificity||This TCTA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-55 amino acids from human TCTA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TCTA Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be required for cellular fusion during osteoclastogenesis.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
May be required for cellular fusion during osteoclastogenesis.
Aplan P.D.,et al.Cancer Res. 55:1917-1921(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Kotake S.,et al.Bone 45:627-639(2009).
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