|Application ||WB, E|
|Calculated MW||36329 Da|
|Other Names||Inactive serine/threonine-protein kinase PLK5, Polo-like kinase 5, PLK-5, PLK5, PLK5P|
|Target/Specificity||This PLK5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-174 amino acids from the Central region of human PLK5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PLK5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.|
|Cellular Location||Nucleus, nucleolus. Cytoplasm|
|Tissue Location||Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Li H.,et al.Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
de Carcer G.,et al.Mol. Cell. Biol. 31:1225-1239(2011).
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