|Application ||WB, E|
|Calculated MW||37948 Da|
|Other Names||Cytosolic 5'-nucleotidase 3A, 22.214.171.124, Cytosolic 5'-nucleotidase 3, Cytosolic 5'-nucleotidase III, cN-III, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I, Uridine 5'-monophosphate hydrolase 1, p36, NT5C3A, NT5C3, P5N1, UMPH1|
|Target/Specificity||This NT5C3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-313 amino acids from human NT5C3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NT5C3, P5N1, UMPH1|
|Function||Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP) (PubMed:24603684). CMP seems to be the preferred substrate (PubMed:15968458).|
|Tissue Location||Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver.|
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Provided below are standard protocols that you may find useful for product applications.
Can act both as nucleotidase and as phosphotransferase.
Amici A.,et al.Blood 96:1596-1598(2000).
Marinaki A.M.,et al.Blood 97:3327-3332(2001).
Kanno H.,et al.Br. J. Haematol. 126:265-271(2004).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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