|Application ||WB, E|
|Calculated MW||123434 Da|
|Other Names||Leucine-rich repeats and immunoglobulin-like domains protein 3, LIG-3, LRIG3, LIG3|
|Target/Specificity||This LRIG3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from human LRIG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRIG3 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).
Guo D.,et al.Genomics 84:157-165(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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