|Application ||WB, E|
|Other Accession||Q3ZBX7, Q865U8|
|Calculated MW||36252 Da|
|Other Names||Ankyrin repeat domain-containing protein 1, Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein, ANKRD1, C193, CARP, HA1A2|
|Target/Specificity||This ANKRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-34 amino acids from human ANKRD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ANKRD1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C193, CARP, HA1A2|
|Function||May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.|
|Tissue Location||Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.|
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May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Chu W.,et al.J. Biol. Chem. 270:10236-10245(1995).
Park J.-H.,et al.Cancer Res. 65:2804-2814(2005).
Deloukas P.,et al.Nature 429:375-381(2004).
Miller M.K.,et al.J. Mol. Biol. 333:951-964(2003).
Cinquetti R.,et al.Hum. Mutat. 29:468-474(2008).
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