|Application ||WB, E|
|Calculated MW||48886 Da|
|Other Names||Lysophosphatidic acid phosphatase type 6, 126.96.36.199, Acid phosphatase 6, lysophosphatidic, Acid phosphatase-like protein 1, PACPL1, ACP6, ACPL1, LPAP|
|Target/Specificity||This ACP6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 251-283 amino acids from the Central region of human ACP6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACP6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.|
|Tissue Location||Highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and weakly expressed in thymus and colon.|
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Provided below are standard protocols that you may find useful for product applications.
Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.
Hiroyama M.,et al.J. Biol. Chem. 274:29172-29180(1999).
Takayama I.,et al.Gut 50:790-796(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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