|Application ||WB, E|
|Calculated MW||113010 Da|
|Other Names||Protein transport protein Sec24D, SEC24-related protein D, SEC24D, KIAA0755|
|Target/Specificity||This SEC24D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-266 amino acids from human SEC24D.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SEC24D Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.|
|Cellular Location||Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane|
|Tissue Location||Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver|
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Provided below are standard protocols that you may find useful for product applications.
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Tang B.L.,et al.Biochem. Biophys. Res. Commun. 258:679-684(1999).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bonnon C.,et al.J. Cell Sci. 123:1705-1715(2010).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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