|Application ||WB, E|
|Other Accession||Q9TSX8, Q9Z0K8|
|Calculated MW||57012 Da|
|Other Names||Pantetheinase, 22.214.171.124, Pantetheine hydrolase, Tiff66, Vascular non-inflammatory molecule 1, Vanin-1, VNN1|
|Target/Specificity||This VNN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 143-175 amino acids from human VNN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VNN1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.|
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Provided below are standard protocols that you may find useful for product applications.
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Galland F.,et al.Genomics 53:203-213(1998).
Prehn S.,et al.Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Maras B.,et al.FEBS Lett. 461:149-152(1999).
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