MTUS2 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q5JR59 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 150195 Da |
Gene ID | 23281 |
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Other Names | Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Microtubule plus-end tracking protein TIP150, Tracking protein of 150 kDa, MTUS2, CAZIP, KIAA0774, TIP150 |
Target/Specificity | This MTUS2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 917-949 amino acids from human MTUS2. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MTUS2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MTUS2 |
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Synonyms | CAZIP, KIAA0774, TIP150 |
Function | Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. |
Cellular Location | Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules |
Tissue Location | Detected in embryonic stem cells differentiating to cardiomyocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
References
Nagase T.,et al.DNA Res. 5:277-286(1998).
Ohara O.,et al.Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Du Puy L.,et al.Dev. Dyn. 238:2903-2911(2009).
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