|Application ||WB, E|
|Other Accession||O18875, Q8VBW1, P28570|
|Calculated MW||70523 Da|
|Other Names||Sodium- and chloride-dependent creatine transporter 1, CT1, Creatine transporter 1, Solute carrier family 6 member 8, SLC6A8|
|Target/Specificity||This SLC6A8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from human SLC6A8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC6A8 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the uptake of creatine in muscles and brain.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate|
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Provided below are standard protocols that you may find useful for product applications.
Required for the uptake of creatine in muscles and brain.
Nash S.R.,et al.Recept. Channels 2:165-174(1994).
Sora I.,et al.Biochem. Biophys. Res. Commun. 204:419-427(1994).
Sandoval N.,et al.Genomics 35:383-385(1996).
Barnwell L.F.,et al.Gene 159:287-288(1995).
Martinez-Munoz C.,et al.Gene 418:53-59(2008).
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