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NAA40 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86UY6 |
| Other Accession | Q8VE10 |
| Reactivity | Human, Mouse |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27194 Da |
| Gene ID | 79829 |
|---|---|
| Other Names | N-alpha-acetyltransferase 40, 2.3.1.-, N-acetyltransferase 11, NatD catalytic subunit, NAA40, NAT11 |
| Target/Specificity | This NAA40 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 179-222 amino acids from the human region of human NAA40. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NAA40 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAA40 {ECO:0000303|PubMed:19660095, ECO:0000312|HGNC:HGNC:25845} |
|---|---|
| Function | N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha- acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity). |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Polevoda B.,et al.BMC Proc. 3:S2-S2(2009).
Hole K.,et al.PLoS ONE 6:E24713-E24713(2011).
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