|Application ||FC, IHC-P, WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||50819 Da|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 8, Glucose transporter type 8, GLUT-8, Glucose transporter type X1, SLC2A8, GLUT8, GLUTX1|
|Target/Specificity||This SLC2A8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 260-292 amino acids from the Central region of human SLC2A8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC2A8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity)|
|Tissue Location||Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues|
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Provided below are standard protocols that you may find useful for product applications.
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).
Doege H.,et al.J. Biol. Chem. 275:16275-16280(2000).
Ibberson M.R.,et al.J. Biol. Chem. 275:4607-4612(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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