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PI4KA Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | E9Q3L2 |
| Other Accession | P42356, O02811, O08662 |
| Reactivity | Mouse |
| Predicted | Bovine, Human, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 237042 Da |
| Antigen Region | 1460-1490 aa |
| Gene ID | 224020 |
|---|---|
| Other Names | Phosphatidylinositol 4-kinase alpha, PI4-kinase alpha, PI4K-alpha, PtdIns-4-kinase alpha, 2.7.1.67, PI4KA, PIK4, PIK4CA |
| Target/Specificity | This PI4KA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1460-1490 amino acids of mouse PI4KA. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PI4KA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pi4ka {ECO:0000312|MGI:MGI:2448506} |
|---|---|
| Synonyms | Pik4, Pik4ca |
| Function | Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P42356}. Cell membrane {ECO:0000250|UniProtKB:P42356}. Note=Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and HYCC (HYCC1 or HYCC2) Localization to the plasma membrane is regulated by TMEM150A {ECO:0000250|UniProtKB:P42356} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate.
References
Wong K.,et al.J. Biol. Chem. 269:28878-28884(1994).
Gehrmann T.,et al.Biochim. Biophys. Acta 1437:341-356(1999).
Dunham I.,et al.Nature 402:489-495(1999).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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