|Application ||WB, E|
|Other Accession||Q646A1, Q646E4, Q646C3, Q645V7|
|Calculated MW||34558 Da|
|Other Names||Taste receptor type 2 member 50, T2R50, Taste receptor type 2 member 51, T2R51, TAS2R50|
|Target/Specificity||This TAS2R50 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-222 amino acids from human TAS2R50.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TAS2R50 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells|
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Provided below are standard protocols that you may find useful for product applications.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Bufe B.,et al.Nat. Genet. 32:397-401(2002).
Conte C.,et al.Cytogenet. Genome Res. 98:45-53(2002).
Fischer A.,et al.Mol. Biol. Evol. 22:432-436(2005).
Scherer S.E.,et al.Nature 440:346-351(2006).
Montmayeur J.-P.,et al.Curr. Opin. Neurobiol. 12:366-371(2002).
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