|Application ||WB, E|
|Other Accession||Q646A1, Q646E4, Q646C3, Q645V7|
|Calculated MW||34558 Da|
|Other Names||Taste receptor type 2 member 50, T2R50, Taste receptor type 2 member 51, T2R51, TAS2R50|
|Target/Specificity||This TAS2R50 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-222 amino acids from human TAS2R50.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TAS2R50 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Bufe B.,et al.Nat. Genet. 32:397-401(2002).
Conte C.,et al.Cytogenet. Genome Res. 98:45-53(2002).
Fischer A.,et al.Mol. Biol. Evol. 22:432-436(2005).
Scherer S.E.,et al.Nature 440:346-351(2006).
Montmayeur J.-P.,et al.Curr. Opin. Neurobiol. 12:366-371(2002).
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