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LRCH4 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75427 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73450 Da |
| Gene ID | 4034 |
|---|---|
| Other Names | Leucine-rich repeat and calponin homology domain-containing protein 4, Leucine-rich repeat neuronal protein 4, Leucine-rich neuronal protein, LRCH4, LRN, LRRN1, LRRN4 |
| Target/Specificity | This LRCH4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 305-348 amino acids from the Central region of human LRCH4. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LRCH4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRCH4 (HGNC:6691) |
|---|---|
| Synonyms | LRN, LRRN1, LRRN4 |
| Function | Accessory protein that regulates signaling by multiple TLRs, acting as a broad-spanning regulator of the innate immune response. In macrophages, binds LPS and promotes proper docking of LPS in lipid raft membrane. May be required for lipid raft maintenance. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q921G6}; Single-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Gloeckner G.,et al.Genome Res. 8:1060-1073(1998).
Scherer S.W.,et al.Science 300:767-772(2003).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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