|Application ||WB, E|
|Other Accession||Q921T2, Q5PQX1|
|Calculated MW||66248 Da|
|Other Names||Torsin-1A-interacting protein 1, Lamin-associated protein 1B, LAP1B, TOR1AIP1, LAP1|
|Target/Specificity||This TOR1AIP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 42-76 amino acids from human TOR1AIP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TOR1AIP1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.|
|Cellular Location||Nucleus inner membrane; Single-pass membrane protein|
|Tissue Location||Expressed in muscle, liver and kidney.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Kondo Y.,et al.Biochem. Biophys. Res. Commun. 294:770-778(2002).
Goodchild R.E.,et al.J. Cell Biol. 168:855-862(2005).
If you have any additional inquiries please email technical services at firstname.lastname@example.org.