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NOP2 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NOP2 Antibody (N-Term) AP22191a
    All lanes : Anti-NOP2 Antibody (N-Term) at 1:2000 dilution Lane 1: K562 whole cell lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 89 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P46087
Other Accession Q922K7
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 89302 Da
Additional Information
Gene ID 4839
Other Names Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase, 2.1.1.-, Nucleolar protein 1, Nucleolar protein 2 homolog, Proliferating-cell nucleolar antigen p120, Proliferation-associated nucleolar protein p120, NOP2, NOL1, NSUN1
Target/Specificity This NOP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 9-43 amino acids from human NOP2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNOP2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOP2
Synonyms NOL1, NSUN1
Function S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)

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Background

S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation.

References

Fonagy A.,et al.Cancer Commun. 1:243-251(1989).
Larson R.G.,et al.Cancer Commun. 2:63-71(1990).
Valdez B.C.,et al.Cancer Res. 52:5681-5686(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).

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$ 295.00
$ 99.00
Cat# AP22191a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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