ADAMTS20 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P59510 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 214721 Da |
Gene ID | 80070 |
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Other Names | A disintegrin and metalloproteinase with thrombospondin motifs 20, ADAM-TS 20, ADAM-TS20, ADAMTS-20, 3.4.24.-, ADAMTS20 |
Target/Specificity | This ADAMTS20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 782-816 amino acids from the Central region of human ADAMTS20. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADAMTS20 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADAMTS20 |
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Function | May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain. |
Cellular Location | Secreted, extracellular space, extracellular matrix |
Tissue Location | Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain.
References
Somerville R.P.,et al.J. Biol. Chem. 278:9503-9513(2003).
Llamazares M.,et al.J. Biol. Chem. 278:13382-13389(2003).
Scherer S.E.,et al.Nature 440:346-351(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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