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TOMM40 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IF, E |
|---|---|
| Primary Accession | O96008 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37893 Da |
| Gene ID | 10452 |
|---|---|
| Other Names | Mitochondrial import receptor subunit TOM40 homolog, Protein Haymaker, Translocase of outer membrane 40 kDa subunit homolog, p38.5, TOMM40, C19orf1, PEREC1, TOM40 |
| Target/Specificity | This TOMM40 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-56 amino acids from human TOMM40. |
| Dilution | IF~~1:25 WB~~1:2000 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TOMM40 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TOMM40 |
|---|---|
| Synonyms | C19orf1, PEREC1, TOM40 |
| Function | Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022). |
| Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Note=Associates with the mitochondria- associated ER membrane via interaction with BCAP31 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Channel-forming protein essential for import of protein precursors into mitochondria.
References
Freitas E.M.,et al.DNA Seq. 9:89-100(1998).
Yoshiura K.,et al.Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Das B.,et al.Int. J. Cancer 94:800-806(2001).
Lubec G.,et al.Submitted (MAR-2007) to UniProtKB.
Johnston A.J.,et al.J. Biol. Chem. 277:42197-42204(2002).
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