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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARL1 Antibody (N-term)   

ARL1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARL1 Antibody (N-term) AP2304A
    Western blot analysis of hARL1-G3 (Cat. #AP2304a) in K562 cell line lysates (35ug/lane). ARL1 (arrow) was detected using the purified Pab.
  • IHC-P - ARL1 Antibody (N-term) AP2304A
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40616
Other Accession P61212, P61211, Q2YDM1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20418 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 400
Other Names ADP-ribosylation factor-like protein 1, ARL1
Target/Specificity This ARL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ARL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARL1
Function GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.
Cellular Location Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Research Areas
Citations (0)

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ARL1 belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.


Hong, J.X., et al., J. Biol. Chem. 273(25):15872-15876 (1998).
Zhang, G.F., et al., J. Biol. Chem. 270(1):21-24 (1995).

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$ 295.00
$ 99.00
Cat# AP2304A
(40 western blots)
Availability: In Stock
Bulk Size
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