ART1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 2
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P52961 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36335 Da |
Antigen Region | 14-43 aa |
Gene ID | 417 |
---|---|
Other Names | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, ADP-ribosyltransferase C2 and C3 toxin-like 1, ARTC1, Mono(ADP-ribosyl)transferase 1, CD296, ART1 |
Target/Specificity | This ART1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human ART1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ART1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ART1 |
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Function | Has ADP-ribosyltransferase activity toward GLP1R. |
Cellular Location | Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor |
Provided below are standard protocols that you may find useful for product applications.
Background
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence of ART1 consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins.
References
Koch-Nolte, F., et al., Genomics 39(3):370-376 (1997). Koch-Nolte, F., et al., Genomics 36(1):215-216 (1996). Okazaki, I.J., et al., Biochemistry 33(43):12828-12836 (1994).
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