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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MGAT1 Antibody (C-term)   

MGAT1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MGAT1 Antibody (C-term) AP2406b
    Western blot analysis of anti-hMGAT1-R426 Pab (Cat. #AP2406b) in Y79 cell line lysate. hMGAT1-R426(arrow) was detected using the purified Pab.
  • IHC-P - MGAT1 Antibody (C-term) AP2406b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26572
Other Accession NP_002397
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50878 Da
Additional Information
Gene ID 4245
Other Names Alpha-1, 3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I, MGAT1, GGNT1, GLCT1, GLYT1, MGAT
Target/Specificity This MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MGAT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMGAT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGAT1
Synonyms GGNT1, GLCT1, GLYT1, MGAT
Function Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Appears to be present in all tissues.
Research Areas
Citations (0)

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There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. MGAT1 (UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I) is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis.


Tan, J., et al., Eur. J. Biochem. 231(2):317-328 (1995).
Kumar, R., et al., Glycobiology 2(4):383-393 (1992).
Hull, E., et al., Biochem. Biophys. Res. Commun. 176(2):608-615 (1991).
Kumar, R., et al., Proc. Natl. Acad. Sci. U.S.A. 87(24):9948-9952 (1990).
Yip, B., et al., Biochem. J. 321 (Pt 2), 465-474 (1997).

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Cat# AP2406b
(40 western blots)
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