- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
ACOX1 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP2523a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ACOX1 Antibody (N-term) - Product info | |
| Application | IHC
|
| Primary Accession | Q15067 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 74424 Da |
ACOX1 Antibody (N-term) - Additional info | |
| Gene ID 51 | |
| Other Names ACOX1; ACOX; Peroxisomal acyl-coenzyme A oxidase 1; Palmitoyl-CoA oxidase; Straight-chain acyl-CoA oxidase | |
| Target/Specificity This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~43 amino acids from the N-terminal region of human ACOX1. | |
| Dilution IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACOX1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACOX1 Antibody (N-term) - Protein Information | |
| Name ACOX1 | |
| Synonyms ACOX | |
| Function Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA | |
| Cellular Location Peroxisome. | |
| Tissue Location Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart | |
ACOX1 Antibody (N-term) - Related products
AM1847a: ACOX1 Antibody (Ascites)
AP2523a: ACOX1 Antibody (N-term)
AP2523b: ACOX1 Antibody (C-term)
RI10070: ACOX1 predesign siRNA
DC02927: Human ACOX1 cDNA Clone
LY12313a: ACOX1 Over-expression Lysate
ACOX1 Antibody (N-term) - Application data
-
ACOX1 Antibody (N-term) (Cat. #AP2523A)immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACOX1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ACOX1 Antibody (N-term) - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.
REFERENCES
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Chu, R., et al., J. Biol. Chem. 270(9):4908-4915 (1995). Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198(3):1113-1118 (1994). Fournier, B., et al., J. Clin. Invest. 94(2):526-531 (1994). Varanasi, U., et al., Proc. Natl. Acad. Sci. U.S.A. 91(8):3107-3111 (1994).
