- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
ZBRK1 (Center) AntibodyPurified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP2547a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ZBRK1 (Center) Antibody - Product info | |
| Application | WB
|
| Primary Accession | Q9GZX5 |
| Other Accession | Q6PF04, Q8NDW4 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 60011 Da |
ZBRK1 (Center) Antibody - Additional info | |
| Gene ID 59348 | |
| Other Names ZNF350; ZBRK1; Zinc finger protein 350; KRAB zinc finger protein ZFQR; Zinc finger and BRCA1-interacting protein with a KRAB domain 1; Zinc finger protein ZBRK1 | |
| Target/Specificity This ZBRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244~273 amino acids from the center region of human ZBRK1. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ZBRK1 (Center) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ZBRK1 (Center) Antibody - Protein Information | |
| Name ZNF350 | |
| Synonyms ZBRK1 | |
| Function Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3 | |
| Cellular Location Nucleus matrix. Note=Associated with the nuclear matrix | |
| Tissue Location Widely expressed. | |
ZBRK1 (Center) Antibody - Related products
AP2547a: ZBRK1 (Center) Antibody
AP2547b: ZBRK1 (C-term) Antibody
RI15834: ZNF350 predesign siRNA
DC02808: Human ZNF350 cDNA Clone
ZBRK1 (Center) Antibody - Application data
-
Western blot analysis of ZBRK1 (Center) Antibody (Cat.# AP2547a) in HL60 cell line lysates (35ug/lane). ZBRK1 (arrow) was detected using the purified Pab.
ZBRK1 (Center) Antibody - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ZBRK1 binds to a specific sequence, GGGxxxCAGxxxTTT, within GADD45 intron 3 that supports the assembly of a nuclear complex minimally containing both ZBRK1 and BRCA1. Through this recognition sequence, ZBRK1 represses transcription in a BRCA1-dependent manner. The results revealed a novel corepressor function for BRCA1 and provided a mechanistic basis for the biologic activity of BRCA1 through sequence-specific transcriptional regulation.
REFERENCES
Liao, G., et al., J. Virol. 79(1):245-256 (2005). Tan, W., et al., J. Biol. Chem. 279(8):6576-6587 (2004). Yun, J., et al., Mol. Cell. Biol. 23(20):7305-7314 (2003). Rutter, J.L., et al., Hum. Mutat. 22(2):121-128 (2003). Ran, Q., et al., Exp. Cell Res. 263(1):156-162 (2001).
