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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PAPSS1 Antibody (N-term K9)   

PAPSS1 Antibody (N-term K9)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PAPSS1 Antibody (N-term K9) AP2607a
    Western blot analysis of PAPSS1 antibody (N-term K9) (Cat.# AP2607a) in CEM cell line lysates (35ug/lane). PAPSS1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43252
Other Accession Q60967, NP_005434
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70833 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 9061
Other Names Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPS synthase 1, PAPSS 1, Sulfurylase kinase 1, SK 1, SK1, Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT, Adenylyl-sulfate kinase, 3'-phosphoadenosine-5'-phosphosulfate synthase, APS kinase, Adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenylylsulfate 3'-phosphotransferase, PAPSS1, ATPSK1, PAPSS
Target/Specificity This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAPSS1 Antibody (N-term K9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ATPSK1, PAPSS
Function Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
Tissue Location Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver Also expressed in high endothelial venules (HEV) cells and in cartilage
Research Areas
Citations ( 0 )


Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.


Venkatachalam, K.V., IUBMB Life 55(1):1-11 (2003).
Xu, Z.H., et al., Biochem. Biophys. Res. Commun. 268(2):437-444 (2000).
Venkatachalam, K.V., et al., J. Biol. Chem. 273(30):19311-19320 (1998).
ul Haque, M.F., et al., Nat. Genet. 20(2):157-162 (1998).
Girard, J.P., et al., FASEB J. 12(7):603-612 (1998).

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$ 295.00
$ 99.00
Cat# AP2607a
(40 western blots)
Availability: In Stock
Bulk Size
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