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SULT4A1a/b Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SULT4A1a/b Antibody (N-term) AP2610a
    Western blot analysis of lysate from human brain tissue lysate, using SULT4A1a/b Antibody (M1)(Cat. #AP2610a). AP2610a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BR01
Other Accession NP_795343
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33085 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 25830
Other Names Sulfotransferase 4A1, ST4A1, 282-, Brain sulfotransferase-like protein, hBR-STL, hBR-STL-1, Nervous system sulfotransferase, NST, SULT4A1, SULTX3
Target/Specificity This SULT4A1a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SULT4A1a/b.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSULT4A1a/b Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SULT4A1
Synonyms SULTX3
Function Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe, slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030)
Research Areas
Citations (0)

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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. SULT4A1 isoforms a and b are selectively expressed in brain tissue. Isoform a is the predominant of the two isoforms of this protein. Isoform b includes an alternate segment, compared to isoform a, that causes a frameshift. The resulting protein (isoform b) has a distinct and shorter C-terminus when compared to isoform a.


Liyou, N.E., et al., J. Histochem. Cytochem. 51(12):1655-1664 (2003).
Weinshilboum, R.M., et al., FASEB J. 11(1):3-14 (1997).
Glatt, H., et al., Mutat. Res. 482 (1-2), 27-40 (2001).
Sakakibara, Y., et al., Gene 285 (1-2), 39-47 (2002).
Glatt, H., et al., Toxicol. Lett. 112-113, 341-348 (2000).

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$ 295.00
$ 99.00
Cat# AP2610a
(40 western blots)
Availability: In Stock
Bulk Size
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