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Msx2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Msx2 Antibody (N-term) AP2709a
    Western blot analysis of Msx2 (arrow) using rabbit polyclonal Msx2 Antibody (Human N-term) (Cat.#AP2709a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2) (Origene Technologies).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35548
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28897 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 4488
Other Names Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Target/Specificity This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Msx2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMsx2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSX2
Synonyms HOX8
Function Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Msx2 is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in the Msx2 gene are associated with parietal foramina 1 and craniosynostosis type 2.


Shao,J.S., Ann. N. Y. Acad. Sci. 1117, 40-50 (2007)
Han,J., Mech. Dev. 124 (9-10), 729-745 (2007)
Ghassibe,M., Eur. J. Pediatr. 165 (10), 734-735 (2006)

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$ 295.00
$ 99.00
Cat# AP2709a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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