|Application ||WB, IHC-P, E|
|Calculated MW||41528 Da|
|Antigen Region||347-376 aa|
|Other Names||Wnt inhibitory factor 1, WIF-1, WIF1|
|Target/Specificity||This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human WIF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WIF1 Antibody(Human C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.|
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Provided below are standard protocols that you may find useful for product applications.
WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.
Elston,M.S., Endocrinology 149 (3), 1235-1242 (2008)
Clement,G., Cancer Sci. 99 (1), 46-53 (2008)
Chan,S.L., Lab. Invest. 87 (7), 644-650 (2007)
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