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SEMA6A Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEMA6A Antibody (C-term) AP2740b
    Western blot analysis of SEMA6A Antibody (C-term) Pab (Cat. #AP2740b) pre-incubated without(lane 1) and with(lane 2) blocking peptide in HL-60 cell line lysate. SEMA6A (arrow) was detected using the purified Pab.
  • WB - SEMA6A Antibody (C-term) AP2740b
    Western blot analysis of anti-SEMA6A Antibody (C-term)(Cat.#AP2740b) pre-incubated with(right lane) and without(left lane) blocking peptide in mouse cerebellum tissue lysate. SEMA6A (arrow) was detected using the purified Pab.
  • IHC-P - SEMA6A Antibody (C-term) AP2740b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with SEMA6A antibody (C-term) (Cat.#AP2740b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2E6
Other Accession O35464
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 114395 Da
Antigen Region 998-1028 aa
Additional Information
Gene ID 57556
Other Names Semaphorin-6A, Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A-1, SEMA6A, KIAA1368, SEMAQ
Target/Specificity This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 998-1028 amino acids from the C-terminal region of human SEMA6A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEMA6A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1368, SEMAQ
Function Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.


Prislei,S., Mol. Cancer Ther. 7 (1), 233-241 (2008)
Katoh,M., Int. J. Mol. Med. 20 (3), 405-409 (2007)
Gautier,G., Am. J. Pathol. 168 (2), 453-465 (2006)

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$ 295.00
$ 99.00
Cat# AP2740b
(40 western blots)
Availability: In Stock
Bulk Size
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