- CITATIONS: 1
|Application ||WB, E|
|Other Accession||P70623, O97788, P04117, P48035|
|Reactivity||Human, Mouse, Rat|
|Predicted||Rat, Pig, Bovine|
|Calculated MW||14719 Da|
|Antigen Region||1-30 aa|
|Other Names||Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4|
|Target/Specificity||This FABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human FABP4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FABP4 Antibody (Y20) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity)|
Provided below are standard protocols that you may find useful for product applications.
FABP4 is a fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
Cabre,A., J. Lipid Res. 49 (8), 1746-1751 (2008)
Fasshauer,M., Am. J. Hypertens. 21 (5), 582-586 (2008)
Cabre,A., Clin. Chem. 54 (1), 181-187 (2008)
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