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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   SSB Antibody (N-term)   

SSB Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SSB Antibody (N-term) AP2801a
    Western blot analysis of anti-SSB Antibody (N-term) (Cat. #AP2801a) in 293 cell line lysates (35ug/lane).SSB(arrow) was detected using the purified Pab.
  • IHC-P - SSB Antibody (N-term) AP2801a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SSB Antibody (N-term)(Cat. #AP2801a) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - SSB Antibody (N-term) AP2801a
    SSB Antibody (N-term) (Cat. #AP2801a) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05455
Other Accession P10881
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46837 Da
Antigen Region 66-96 aa
Additional Information
Gene ID 6741
Other Names Lupus La protein, La autoantigen, La ribonucleoprotein, Sjoegren syndrome type B antigen, SS-B, SSB
Target/Specificity This SSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SSB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSB
Function Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Cellular Location Nucleus.
Research Areas
Citations ( 0 )


SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. This protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.


Bitko,V., J. Virol. 82 (16), 7977-7987 (2008) Kotik-Kogan,O., Structure 16 (6), 852-862 (2008) Biswas,D., Clin. Rheumatol. 27 (6), 717-722 (2008)

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$ 295.00
$ 99.00
Cat# AP2801a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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