|Application ||WB, E|
|Calculated MW||11740 Da|
|Antigen Region||1-30 aa|
|Other Names||Protein S100-A11, Calgizzarin, Metastatic lymph node gene 70 protein, MLN 70, Protein S100-C, S100 calcium-binding protein A11, Protein S100-A11, N-terminally processed, S100A11, MLN70, S100C|
|Target/Specificity||This S100A11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human S100A11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||S100A11 Antibody (S6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Facilitates the differentiation and the cornification of keratinocytes.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
S100A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of S100A11 gene have been implicated in tumor metastasis.
Fernandez-Fernandez,M.R., Protein Sci. 17 (10), 1663-1670 (2008)
Kouno,T., J. Pept. Sci. 14 (10), 1129-1138 (2008)
Cecil,D.L., J. Immunol. 180 (12), 8378-8385 (2008)
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