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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TRAIP Antibody (C-term)   

TRAIP Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRAIP Antibody (C-term) AP2820b
    Western blot analysis of anti-TRAIP Antibody (C-term) (Cat.#AP2820b) in HepG2 cell line lysates (35ug/lane). TRAIP(arrow) was detected using the purified Pab.
  • IHC-P - TRAIP Antibody (C-term) AP2820b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TRAIP antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BWF2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53294 Da
Antigen Region 328-356 aa
Additional Information
Gene ID 10293
Other Names E3 ubiquitin-protein ligase TRAIP, 632-, RING finger protein 206, TRAF-interacting protein, TRAIP, RNF206, TRIP
Target/Specificity This TRAIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-356 amino acids from the C-terminal region of human TRAIP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRAIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RNF206, TRIP
Function Inhibits activation of NF-kappa-B mediated by TNF (By similarity). Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFN-beta production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation. May mediate assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN to facilitate bypass of DNA lesions and preserve genomic integrity.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Nucleus, nucleolus. Note=Occasionally observed at nuclear puncta
Research Areas
Citations (0)

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TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.


Wu,C., Proteomics 7 (11), 1775-1785 (2007) Regamey,A., J. Exp. Med. 198 (12), 1959-1964 (2003)

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$ 295.00
$ 99.00
Cat# AP2820b
(40 western blots)
Availability: In Stock
Bulk Size
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