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>   home   >   Products   >   Primary Antibodies   >   SNRPC Antibody (C-term)   

SNRPC Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNRPC Antibody (C-term) AP2841b
    Western blot analysis of anti-SNRPC Antibody (C-term) (Cat.#AP2841b) in K562 cell line lysates (35ug/lane). SNRPC(arrow) was detected using the purified Pab.
  • IHC-P - SNRPC Antibody (C-term) AP2841b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with SNRPC Antibody (C-term) (Cat.#AP2841b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - SNRPC Antibody (C-term) AP2841b
    SNRPC Antibody (C-term) (Cat. #AP2841b) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09234
Other Accession D3ZCL3, Q62241, E1C6F0, Q32PA0
Reactivity Human
Predicted Bovine, Chicken, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17394 Da
Antigen Region 133-159 aa
Additional Information
Gene ID 6631
Other Names U1 small nuclear ribonucleoprotein C {ECO:0000255|HAMAP-Rule:MF_03153}, U1 snRNP C {ECO:0000255|HAMAP-Rule:MF_03153}, U1-C {ECO:0000255|HAMAP-Rule:MF_03153}, U1C {ECO:0000255|HAMAP-Rule:MF_03153}, SNRPC {ECO:0000255|HAMAP-Rule:MF_03153}
Target/Specificity This SNRPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human SNRPC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRPC Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNRPC {ECO:0000255|HAMAP-Rule:MF_03153}
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Cellular Location Nucleus.
Citations (0)

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SNRPC is associated with snRNP U1.


Hochleitner,E.O., J. Biol. Chem. 280 (4), 2536-2542 (2005)
Muto,Y., J. Mol. Biol. 341 (1), 185-198 (2004)
Forch,P., EMBO J. 21 (24), 6882-6892 (2002)
Gunnewiek,J.M., Nucleic Acids Res. 23 (23), 4864-4871 (1995)

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$ 295.00
$ 99.00
Cat# AP2841b
(40 western blots)
Availability: In Stock
Bulk Size
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