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SNRPD1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNRPD1 Antibody (Center) AP2842c
    All lanes : Anti-SNRPD1 Antibody (Center) at 1:1000 dilution Lane 1: HL-60 whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 13 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - SNRPD1 Antibody (Center) AP2842c
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with SNRPD1 Antibody (Center) (Cat.#AP2842c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - SNRPD1 Antibody (Center) AP2842c
    SNRPD1 Antibody (Center) (Cat. #AP2842c) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62314
Other Accession P62315, Q4R5F6, Q3ZC10
Reactivity Human
Predicted Bovine, Monkey, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13282 Da
Antigen Region 46-78 aa
Additional Information
Gene ID 6632
Other Names Small nuclear ribonucleoprotein Sm D1, Sm-D1, Sm-D autoantigen, snRNP core protein D1, SNRPD1
Target/Specificity This SNRPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-78 amino acids from the Central region of human SNRPD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRPD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes
Research Areas
Citations (0)

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SNRPD1 is a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. This protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA.


Lehner,B., Genome Res. 14 (7), 1315-1323 (2004)
Will,C.L., RNA 10 (6), 929-941 (2004)

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$ 295.00
$ 99.00
Cat# AP2842c
(40 western blots)
Availability: In Stock
Bulk Size
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