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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   TRIP13 Antibody (N-term)   

TRIP13 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRIP13 Antibody (N-term) AP2843a
    Western blot analysis of TRIP13 Antibody (N-term) (Cat.#AP2843a) in K562, Hela, 293 cell line lysates (35ug/lane). TRIP13 (arrow) was detected using the purified Pab.
  • IHC-P - TRIP13 Antibody (N-term) AP2843a
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with TRIP13 Antibody (N-term) (Cat.#AP2843a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - TRIP13 Antibody (N-term) AP2843a
    TRIP13 Antibody (N-term) (Cat. #AP2843a) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - TRIP13 Antibody (N-term) AP2843a
    Western blot analysis of TRIP13 (arrow) using rabbit polyclonal TRIP13 Antibody (N-term) (Cat. #AP2843a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TRIP13 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15645
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48551 Da
Antigen Region 64-90 aa
Additional Information
Gene ID 9319
Other Names Pachytene checkpoint protein 2 homolog, Human papillomavirus type 16 E1 protein-binding protein, 16E1-BP, HPV16 E1 protein-binding protein, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13, TRIP13, PCH2
Target/Specificity This TRIP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-90 amino acids from the N-terminal region of human TRIP13.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRIP13 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIP13
Synonyms PCH2
Function Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).
Research Areas
Citations (0)

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TRIP13 specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction.


Rush,J., Nat. Biotechnol. 23 (1), 94-101 (2005)

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Cat# AP2843a
(40 western blots)
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