|Application ||IF, WB, IHC-P, E|
|Calculated MW||69285 Da|
|Antigen Region||163-191 aa|
|Other Names||Leukotriene A-4 hydrolase, LTA-4 hydrolase, Leukotriene A(4) hydrolase, LTA4H, LTA4|
|Target/Specificity||This LTA4H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human LTA4H.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LTA4H Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.|
|Tissue Location||Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
DHCR24 hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). This enzyme also has some peptidase activity.
Bevan,S., Stroke 40 (3), 696-701 (2009) Crosslin,D.R., Hum. Genet. 125 (2), 217-229 (2009) Huston,A.L., Biochim. Biophys. Acta 1784 (11), 1865-1872 (2008) Rybina,I.V., J. Biol. Chem. 272 (50), 31865-31871 (1997)
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