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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   DCC1 Antibody (N-term)   

DCC1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - DCC1 Antibody (N-term) AP2874a
    Formalin-fixed and paraffin-embedded human brain tissue with DCC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - DCC1 Antibody (N-term) AP2874a
    Western blot analysis of DCC1 antibody (N-term) (Cat.#AP2874a) in mouse heart tissue lysates (35ug/lane). DCC1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BVC3
Other Accession Q14AI0
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44825 Da
Antigen Region 61-87 aa
Additional Information
Gene ID 79075
Other Names Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Target/Specificity This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the N-terminal region of human DCC1.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSCC1
Synonyms DCC1
Function Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
Cellular Location Nucleus.
Research Areas
Citations (0)

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DCC1 is involved in sister chromatid cohesion establishment. The protein may act as a PCNA loader, loading PCNA onto primed templates.


Clark H.F., Gurney A.L.Genome Res. 13:2265-2270(2003)
Merkle C.J., Karnitz L.M.J. Biol. Chem. 278:30051-30056(2003)

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Cat# AP2874a
(40 western blots)
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