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CCT5 Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP2896c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
CCT5 Antibody (Center) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P48643 |
| Other Accession | Q4R6V2 |
| Reactivity | Human |
| Predicted | Monkey |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 59671 Da |
CCT5 Antibody (Center) - Additional info | |
| Gene ID 22948 | |
| Other Names CCT5; CCTE; KIAA0098; T-complex protein 1 subunit epsilon; CCT-epsilon | |
| Target/Specificity This CCT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225~255 amino acids from the Center region of human CCT5. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CCT5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
CCT5 Antibody (Center) - Protein Information | |
| Name CCT5 | |
| Synonyms CCTE, KIAA0098 | |
| Function Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | |
| Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, centrosome | |
CCT5 Antibody (Center) - Related products
AP2896a: CCT5 Antibody (N-term)
AP2896c: CCT5 Antibody (Center)
DC02006: Human CCT5 cDNA Clone
BP2896a: CCT5 Antibody (N-term) Blocking Peptide
CCT5 Antibody (Center) - Application data
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Western blot analysis of CCT5 Antibody (Center) (Cat. #AP2896c) in Hela cell line lysates (35ug/lane). CCT5 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CCT5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Flow cytometric analysis of hela cells using CCT5 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CCT5 Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.
REFERENCES
Zebol,J.R., Int. J. Biochem. Cell Biol. 41 (4), 822-827 (2009)
