|Application ||WB, IHC-P, FC, E|
|Other Accession||A5GFY8, Q61753, Q60HD7, Q5EAD2|
|Predicted||Bovine, Monkey, Pig|
|Calculated MW||56651 Da|
|Antigen Region||140-168 aa|
|Other Names||D-3-phosphoglycerate dehydrogenase, 3-PGDH, PHGDH, PGDH3|
|Target/Specificity||This PHGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the N-terminal region of human PHGDH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PHGDH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
3-Phosphoglycerate dehydrogenase catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
Klomp,L.W., et.al., Am. J. Hum. Genet. 67 (6), 1389-1399 (2000)
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