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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PHGDH Antibody (Center)   

PHGDH Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • IHC-P - PHGDH Antibody (Center) AP2936c
    PHGDH Antibody (Center) (Cat. #AP2936c) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PHGDH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PHGDH Antibody (Center) AP2936c
    PHGDH Antibody (Center) (Cat. #AP2936c) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - PHGDH Antibody (Center) AP2936c
    PHGDH Antibody (Center) (Cat. #AP2936c) western blot analysis in Ramos cell line lysates (15ug/lane).This demonstrates the PHGDH antibody detected the PHGDH protein (arrow).
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC, E
Primary Accession O43175
Other Accession O08651, Q61753, Q60HD7, NP_006614
Reactivity Human
Predicted Monkey, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 56651 Da
Antigen Region 249-277 aa
Additional Information
Gene ID 26227
Other Names D-3-phosphoglycerate dehydrogenase, 3-PGDH, PHGDH, PGDH3
Target/Specificity This PHGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human PHGDH.
Dilution IHC-P~~1:50~100
FC~~1:10~50
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPHGDH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHGDH
Synonyms PGDH3
Research Areas
Citations ( 0 )

Background

3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.

References

Du, H., et al. Reproduction 139(1):237-245(2010)
Burton, R.L., et al. Biochemistry 48(22):4808-4815(2009)
Kim, J.W., et al. Psychiatr. Genet. 19 (3), 161 (2009) :
Tabatabaie, L., et al. Hum. Mutat. 30(5):749-756(2009)

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$ 295.00
$ 99.00
Cat# AP2936c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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