|Application ||WB, IHC-P, FC, E|
|Other Accession||P47239, P23759, P24610|
|Calculated MW||52968 Da|
|Antigen Region||98-126 aa|
|Other Names||Paired box protein Pax-3, HuP2, PAX3, HUP2|
|Target/Specificity||This PAX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human PAX3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAX3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (PubMed:21965087).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
PAX3 probable is a transcription factor associated with development of alveolar rhabdomyosarcoma.
Boutet,S.C., et.al., Cell 130 (2), 349-362 (2007)
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