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Phospho-HNF4A-pS142 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP3590a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Phospho-HNF4A-pS142 Antibody - Product info | |
| Application | DB, IF
|
| Primary Accession | P41235 |
| Other Accession | Q91766, P22449, P49698, NP_849180 |
| Reactivity | Human |
| Predicted | Mouse, Rat, Xenopus |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 52785 Da |
Phospho-HNF4A-pS142 Antibody - Additional info | |
| Gene ID 3172 | |
| Other Names HNF4A; HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; Transcription factor HNF-4 | |
| Target/Specificity This Phospho-HNF4A-pS142 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 125~154 amino acids surrounding S142 of human HNF4A. | |
| Dilution DB~~1:50~100 IF~~1:10~50 | |
| Format This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S142 of human HNF4A. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Phospho-HNF4A-pS142 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Phospho-HNF4A-pS142 Antibody - Protein Information | |
| Name HNF4A | |
| Synonyms HNF4, NR2A1, TCF14 | |
| Function Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine | |
| Cellular Location Nucleus. | |
Phospho-HNF4A-pS142 Antibody - Related products
AP2778a: HNF4A Antibody (S142)
AP2778c: HNF4A Antibody (Center)
AP3590a: Phospho-HNF4A-pS142 Antibody
AP9435a: HNF4A Antibody (N-term)
RI12524: HNF4A predesign siRNA
BP2778a: HNF4A Antibody (S142) Blocking Peptide
BP2778c: HNF4A Antibody (Center) Blocking Peptide
BP3590a: Phospho-HNF4A-pS142 Antibody Blocking Peptide
BP9435a: HNF4A Antibody (N-term) Blocking Peptide
AT2393a: HNF4A Antibody (monoclonal) (M04)
AT2394a: HNF4A Antibody (monoclonal) (M05)
AT2395a: HNF4A Antibody (monoclonal) (M07)
AJ1040a: AMPK-alpha1 Antibody Phospho-pS487
Phospho-HNF4A-pS142 Antibody - Application data
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Dot blot analysis of anti-Phospho-HNF4A-pS142 Antibody (Cat.#AP3590a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
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Confocal immunofluorescent analysis of Phospho-HNF4A-pS142 Antibody(Cat#AP3590a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Phospho-HNF4A-pS142 Antibody - Research Areas
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BACKGROUND
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
REFERENCES
Sugai,M., Pathol. Int. 58 (11), 681-686 (2008) Lee,S.S., Hepatology 48 (2), 635-645 (2008) Guo,H., Biochem. J. 394 (PT 2), 379-387 (2006) Hong,Y.H., J. Biol. Chem. 278 (30), 27495-27501 (2003)