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Phospho-BAR2-pT384 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP3634a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
Phospho-BAR2-pT384 Antibody - Product info | |
| Application | DB
|
| Primary Accession | P07550 |
| Other Accession | NP_000015 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 46459 Da |
Phospho-BAR2-pT384 Antibody - Additional info | |
| Gene ID 154 | |
| Other Names ADRB2; ADRB2R; B2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor | |
| Target/Specificity This Phospho-BAR2-pT384 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 371~401 amino acids surrounding T384 of human BAR2. | |
| Dilution DB~~1:500 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Phospho-BAR2-pT384 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Phospho-BAR2-pT384 Antibody - Protein Information | |
| Name ADRB2 | |
| Synonyms ADRB2R, B2AR | |
| Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine | |
| Cellular Location Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane | |
Phospho-BAR2-pT384 Antibody - Related products
AP3548a: Phospho-BAR2-pS261 Antibody
AP3598a: Phospho-BAR2-pS364 Antibody
AP3634a: Phospho-BAR2-pT384 Antibody
AP7263a: beta 2 Adrenergic Receptor (BAR2) Antibody (N-term)
AP7263e: ADRB2 Antibody (S364)
AP7263f: ADRB2 Antibody (T384)
RI10153: ADRB2 predesign siRNA
DC08360: Human ADRB2 cDNA Clone
BP3548a: Phospho-BAR2-pS261 Antibody Blocking Peptide
BP3598a: Phospho-BAR2-pS364 Antibody Blocking Peptide
BP3634a: Phospho-BAR2-pT384 Antibody Blocking Peptide
BP7263a: BAR2 Antibody (N-term) Blocking Peptide
BP7263d: BAR2 Antibody (S261) Blocking Peptide
BP7263e: ADRB2 Antibody (S364) Blocking Peptide
Phospho-BAR2-pT384 Antibody - Application data
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Dot blot analysis of anti-Phospho-BAR2-pT384 Antibody (Cat.#AP3634a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Phospho-BAR2-pT384 Antibody - Research Areas
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BACKGROUND
Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
REFERENCES
Wolfarth,B., Metab. Clin. Exp. 56 (12), 1649-1651 (2007) Cherezov,V., Science 318 (5854), 1258-1265 (2007)
