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Phospho-APG8c (MAP1LC3C)-Y105 AntibodyPurified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| AP3691a | DISCONTINED INQUIRE CLICK INQUIRE Add to cart | |||
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Product info | |
| Application | DB
|
| Primary Accession | Q9BXW4 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 16852 Da |
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Additional info | |
| Gene ID 440738 | |
| Other Names MAP1LC3C; Microtubule-associated proteins 1A/1B light chain 3C; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; MAP1 light chain 3-like protein 3; MAP1A/MAP1B light chain 3 C; Microtubule-associated protein 1 light chain 3 gamma | |
| Target/Specificity This Phospho-APG8c (MAP1LC3C)-Y105 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 91~121 amino acids surrounding Y105 of human APG8c (MAP1LC3C). | |
| Dilution DB~~1:500 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Phospho-APG8c (MAP1LC3C)-Y105 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Protein Information | |
| Name MAP1LC3C | |
| Function Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity) | |
| Cellular Location Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes | |
| Tissue Location Most abundant in placenta, lung and ovary. | |
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Related products
AP1804a: LC3 Antibody (APG8C) (N-term)
AP1804e: LC3 Antibody (APG8C) (T48)
AP1804f: LC3 Antibody (APG8C) (Y105)
AP3457a: Phospho-LC3C-S9 Antibody
AP3531a: Phospho-LC3C-S137/138 Antibody
AP3646a: Phospho-LC3C-T48 Antibody
AP3691a: Phospho-APG8c (MAP1LC3C)-Y105 Antibody
RI13152: MAP1LC3C predesign siRNA
BP1804a: LC3 Antibody (APG8c) (N-term) Blocking Peptide
BP1804e: APG8c (MAP1LC3C) Antibody (T48) Blocking Peptide
BP1804f: APG8c (MAP1LC3C) Antibody (Y105) Blocking Peptide
BP3457a: Phospho-LC3 (APG8c) - S9 Antibody Blocking Peptide
BP3531a: Phospho-LC3 (APG8c) - S137/138 Antibody Blocking Peptide
BP3646a: Phospho-APG8c (MAP1LC3C)-T48 Antibody Blocking Peptide
BP3647a: Phospho-APG8c (MAP1LC3C)-Y105 Antibody Blocking Peptide
BP3691a: Phospho-APG8c (MAP1LC3C)-Y105 Antibody Blocking Peptide
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Application data
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Dot blot analysis of anti-Phospho-APG8c (MAP1LC3C)-Y105 Phospho-specific Pab (Cat. #AP3691a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Phospho-APG8c (MAP1LC3C)-Y105 Antibody - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
APG8c is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. APG8c is 1 of 3 orthologs of the yeast autophagosome protein Atg8.
REFERENCES
Tanida,I., et.al., J. Biol. Chem. 279 (35), 36268-36276 (2004) He,H., et.al., J. Biol. Chem. 278 (31), 29278-29287 (2003)
