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Phospho-APG3 - cleaved AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP3740a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP3740a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Phospho-APG3 - cleaved Antibody - Product info | |
| Application | DB
|
| Primary Accession | Q9NT62 |
| Other Accession | Q6AZ50, Q9CPX6, Q6PFS7, Q0VCL3 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat, Zebrafish |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 35864 Da |
Phospho-APG3 - cleaved Antibody - Additional info | |
| Gene ID 64422 | |
| Other Names ATG3; APG3; APG3L; Ubiquitin-like-conjugating enzyme ATG3; Autophagy-related protein 3; Protein PC3-96 | |
| Target/Specificity This APG3 - cleaved Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human APG3. | |
| Dilution DB~~1:100~500 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Phospho-APG3 - cleaved Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Phospho-APG3 - cleaved Antibody - Protein Information | |
| Name ATG3 | |
| Synonyms APG3, APG3L | |
| Function E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy ATG7 (E1-like enzyme) facilitates this reaction by forming an E1- E2 complex with ATG3 | |
| Cellular Location Cytoplasm. | |
| Tissue Location Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta | |
Phospho-APG3 - cleaved Antibody - Related products
AP1807a: ATG3 Antibody (N-term)
AP1807b: ATG3 Antibody (C-term)
AP1807c: ATG3 Antibody (C-term K183)
AP3430a: Phospho-ATG3-Y18 Antibody
AP3740a: Phospho-APG3 - cleaved Antibody
DC05417: Human ATG3 cDNA Clone
LY11891a: ATG3 Over-expression Lysate
BP1807a: APG3L Antibody (N-term) Blocking Peptide
BP1807b: APG3L Antibody (C-term) Blocking Peptide
BP1807c: APG3L Antibody (C-term K183) Blocking Peptide
BP1807e: APG3L Antibody (Y18) Blocking Peptide
BP1833a: cleaved-APG3 Antibody Blocking Peptide
Phospho-APG3 - cleaved Antibody - Application data
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Dot blot analysis of anti-APG3-cleaved Pab (Cat. #AP3740a) on nitrocellulose membrane. 50ng of Cleaved-peptide or Non Cleaved-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Phospho-APG3 - cleaved Antibody - Research Areas
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