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phospho-Sox2(S251) Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • DB - phospho-Sox2(S251) Antibody AP3742a
    Dot blot analysis of anti-phospho-Sox2-pS251 Phospho-specific Pab (Cat. #AP3742a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48431
Other Accession P48432, NP_003097.1, P54231
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34310 Da
Additional Information
Gene ID 6657
Other Names Transcription factor SOX-2, SOX2
Target/Specificity This Sox2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S251 of human Sox2.
Dilution DB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsphospho-Sox2(S251) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX2
Function Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)

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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).


Gen, Y., et al. Cancer Genet. Cytogenet. 202(2):82-93(2010)
Ji, J., et al. Hum. Pathol. 41(10):1438-1447(2010)
Fang, X., et al. OMICS 14(4):369-384(2010)
Sholl, L.M., et al. Am. J. Surg. Pathol. 34(8):1193-1198(2010)
Zhang, D., et al. BMC Med. Genet. 11, 116 (2010) :

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$ 295.00
$ 99.00
Cat# AP3742a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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